In vitro activity of BAL9141 against clinical isolates of gram-negative bacteria

Diagn Microbiol Infect Dis. 2004 Jan;48(1):73-5. doi: 10.1016/j.diagmicrobio.2003.09.006.


The minimum inhibitory concentration and minimum bactericidal concentration of BAL9141 against 150 clinical isolates of gram-negative bacteria were determined and compared to those of cefepime and ceftriaxone. BAL9141 exhibited comparable activity to cefepime and ceftriaxone against Haemophilus influenzae, Klebsiella pneumoniae, and extended-spectrum beta-lactamase nonproducing Enterobacter cloacae, and comparable activity to cefepime against Pseudomonas aeruginosa.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cephalosporins / pharmacology*
  • Drug Resistance, Bacterial
  • Gram-Negative Bacteria / classification
  • Gram-Negative Bacteria / drug effects*
  • Humans
  • Microbial Sensitivity Tests
  • Sampling Studies
  • Sensitivity and Specificity


  • Cephalosporins
  • ceftobiprole