Prioritizing treatment outcomes: head and neck cancer patients versus nonpatients

Head Neck. 2004 Feb;26(2):163-70. doi: 10.1002/hed.10367.


Background: Treatment decisions in head and neck cancer (HNC) might involve consideration of uncertain tradeoffs of one late effect against another or increasing toxicity or residual impairment for increased chance of survival. Understanding how patients prioritize potential outcomes, as well as whether these preferences are similar to those of nonpatients, is important to informed decision making and treatment planning.

Methods: Two hundred forty-seven newly diagnosed HNC patients from nine institutions and 131 nonpatients rank ordered a set of 12 potential treatment outcomes (eg, cure; being able to swallow; normal voice) from highest (1) to lowest (12).

Results: Patients and nonpatients were similar with respect to the three items most frequently ranked in the top three, that is, "being cured of cancer," "living as long as possible," and "having no pain" in that order. In contrast, patients more frequently ranked "cure" (90% vs 80%) and less frequently ranked "no pain" (34% vs 52%) in the top three.

Conclusions: Survival seems to be of paramount importance to both patient and nonpatient groups, overshadowing associated toxicities and potential dysfunction. At the same time, patients might be more willing than nonpatients to undergo aggressive treatments and endure acute distress in the interest of potential long-term gains (ie, cure or longer survival).

Publication types

  • Comparative Study
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Attitude to Health*
  • Deglutition / physiology
  • Female
  • Head and Neck Neoplasms / psychology*
  • Head and Neck Neoplasms / therapy
  • Humans
  • Male
  • Mastication / physiology
  • Middle Aged
  • Pain / prevention & control
  • Quality of Life*
  • Speech Intelligibility / physiology
  • Survival Rate
  • Taste / physiology
  • Treatment Outcome
  • Voice / physiology