A rapid method for illustrating features in both coding and non-coding regions of a genome

Bioinformatics. 2004 Apr 12;20(6):982-3. doi: 10.1093/bioinformatics/bth042. Epub 2004 Feb 5.

Abstract

A bitmap display of the Fourier spectra has been developed which allows convenient whole chromosome scanning for genes and other features. Use of a limited sliding window gives rapid visualization and localization of coding regions in the chromosomes, as well as non-coding features such as repetitive DNA. The method works particularly well on organisms with a skewed base composition, to provide an overview of genomic features.

Publication types

  • Evaluation Study

MeSH terms

  • Algorithms*
  • Animals
  • Chromosome Mapping / methods*
  • Computer Graphics*
  • Fourier Analysis
  • Gene Expression Profiling / methods*
  • Genome
  • Open Reading Frames / genetics
  • Plasmodium falciparum / genetics*
  • Sequence Analysis, DNA / methods*
  • Signal Processing, Computer-Assisted*
  • User-Computer Interface*