MRI findings in children infected by Borrelia burgdorferi

Pediatr Neurol. Nov-Dec 1992;8(6):428-31. doi: 10.1016/0887-8994(92)90003-h.

Abstract

Cranial magnetic resonance imaging abnormalities were observed in 8 children (5 boys, 3 girls; ages 4-14 years) with neurologic problems following infection by Borrelia burgdorferi, the etiologic agent of Lyme disease. Neurologic features included headache (6), behavioral changes (5), facial palsy (2), papilledema (2), papilledema with diplopia (1), disturbance of sleep pattern (2), and carpal tunnel syndrome (1). Two MRI studies demonstrated multiple focal areas of increased signal intensity in white matter on long TR (both proton-density and T2-weighted) images.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adolescent
  • Amoxicillin / therapeutic use
  • Borrelia burgdorferi Group*
  • Brain / pathology
  • Cephalexin / therapeutic use
  • Child
  • Child, Preschool
  • Encephalitis / diagnosis*
  • Encephalitis / drug therapy
  • Female
  • Humans
  • Lyme Disease / diagnosis*
  • Lyme Disease / drug therapy
  • Magnetic Resonance Imaging*
  • Male
  • Neurologic Examination / drug effects

Substances

  • Amoxicillin
  • Cephalexin