Assessment of memory complaint in age-associated memory impairment: the MAC-Q

Int Psychogeriatr. Fall 1992;4(2):165-76. doi: 10.1017/s1041610292000991.


Few brief self-report memory questionnaires are available, and non has been well validated. We designed a brief questionnaire, the MAC-Q, to assess age-related memory decline. Validity and reliability of the MAC-Q were assessed in 232 subjects meeting diagnostic criteria for age-associated memory impairment (AAMI). Concurrent validity of the MAC-Q was supported by a significant correlation (r = .41, p < .001) with a lengthy, well-validated memory questionnaire. Multiple regression analysis indicated that memory test scores were significant predictors of MAC-Q scores. MAC-Q scores were not predicted by Hamilton Depression Scale scores, suggesting that memory complaint in AAMI is not related to affective status. Internal consistency and test-retest reliability of the MAC-Q were satisfactory. Our data support the validity and reliability of the MAC-Q, a new brief memory questionnaire. The MAC-Q is of particular relevance to the assessment of AAMI, but should also prove useful in any clinical or research setting requiring a brief index of memory complaint.

Publication types

  • Clinical Trial

MeSH terms

  • Aged
  • Amnesia / diagnosis*
  • Amnesia / drug therapy
  • Amnesia / psychology
  • Female
  • Humans
  • Male
  • Mental Recall* / drug effects
  • Middle Aged
  • Neuropsychological Tests / statistics & numerical data*
  • Psychometrics
  • Reproducibility of Results
  • United States
  • United States Food and Drug Administration