Sensory-motor coordination during grasping and manipulative actions

Curr Opin Neurobiol. 1992 Dec;2(6):815-23. doi: 10.1016/0959-4388(92)90139-c.


Goal-directed grasping and manipulation of objects are human skills that depend on automatic sensory control in which predictive feed-forward mechanisms integrate somatosensory and visual signals with sensory-motor memory systems. Memory representations of physical and task-relevant properties of the object play a pivotal role. Anticipatory strategies are crucial when purposeful actions arise from learned relationships between afferent patterns and efferent commands. The development of even elementary precision grip skills is a protracted process not concluded until early adolescence. Not surprisingly, the neural control of manual actions engages most central nervous system areas known to be involved in motor control.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Fingers / physiology
  • Friction
  • Hand / innervation
  • Hand / physiology*
  • Humans
  • Memory / physiology
  • Motor Activity / physiology*
  • Muscle Contraction / physiology
  • Neural Pathways / physiology
  • Sensation / physiology*
  • Somatosensory Cortex / physiology
  • Thumb / physiology
  • Vision, Ocular
  • Weight-Bearing / physiology