Movement disorders in astrocytomas of the basal ganglia and the thalamus

J Neurol Neurosurg Psychiatry. 1992 Dec;55(12):1162-7. doi: 10.1136/jnnp.55.12.1162.

Abstract

In a series of 225 patients with astrocytomas (grades I-IV) of the basal ganglia and the thalamus, 20 had a movement disorder. In all patients the histological diagnosis was verified by stereotactic biopsy. Tremor was observed in twelve patients, dystonia in eight, chorea in three, and chorea/ballismus and myoclonus in one. The tumour involved the thalamus in 16 patients. Corticospinal tract dysfunction was evident in 70% of the patients with movement disorders and in 73% of those without. Demographic, clinical, histological and neuroradiological data of the patients with a movement disorder were compared with the data of patients without. CT data yielded no differences with respect to the involvement of anatomical structures. Movement disorders were significantly associated with low-grade astrocytomas.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Astrocytoma / diagnosis*
  • Astrocytoma / pathology
  • Astrocytoma / surgery
  • Basal Ganglia / pathology
  • Basal Ganglia Diseases / diagnosis*
  • Basal Ganglia Diseases / pathology
  • Basal Ganglia Diseases / surgery
  • Biopsy
  • Brain Neoplasms / diagnosis*
  • Brain Neoplasms / pathology
  • Brain Neoplasms / surgery
  • Child
  • Child, Preschool
  • Dominance, Cerebral / physiology
  • Female
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Movement Disorders / diagnosis*
  • Movement Disorders / pathology
  • Movement Disorders / surgery
  • Neurologic Examination
  • Thalamic Diseases / diagnosis*
  • Thalamic Diseases / pathology
  • Thalamic Diseases / surgery
  • Thalamus / pathology
  • Tomography, X-Ray Computed