[Plasma interleukin-6 in patients with disseminated intravascular coagulation]

Rinsho Ketsueki. 1992 Dec;33(12):1797-801.
[Article in Japanese]

Abstract

Plasma Interleukin-6 (IL-6) level was measured in 60 patients with disseminated intravascular coagulation (DIC). Plasma IL-6 level was high in patients with DIC, and was particularly high in patients with multiple organ failure (MOF) or poor prognosis. Plasma IL-6 level correlated positively with C-reactive protein in patients without DIC, but not in those with DIC. The increased plasma IL-6 level observed in DIC patients suggests that activation of the immune system is involved in the progression of DIC and in the pathology of organ failure.

Publication types

  • English Abstract

MeSH terms

  • Adult
  • C-Reactive Protein / metabolism
  • Disseminated Intravascular Coagulation / blood*
  • Disseminated Intravascular Coagulation / immunology
  • Female
  • Humans
  • Interleukin-6 / blood*
  • Male
  • Multiple Organ Failure / blood
  • Prognosis

Substances

  • Interleukin-6
  • C-Reactive Protein