Cilia in children with recurrent upper respiratory tract infections: ultrastructural observations

Pediatr Pulmonol. 1992 Dec;14(4):201-5. doi: 10.1002/ppul.1950140402.


We investigated the ultrastructure of nasal cilia in 27 children suffering from recurrent infections of the upper respiratory tract, during and after the onset of an acute respiratory infection, and after a convalescent period of 12 weeks. Our results demonstrated that in seven subjects after resolution of infection, the morphology of a large proportion of the cilia (32%) was not back to normal. These findings suggest a long-term residual effect of infection, or the inability to reestablish normal ciliary structure during the convalescent period in some subjects with recurrent upper respiratory tract infection.

MeSH terms

  • Acute Disease
  • Case-Control Studies
  • Child
  • Child, Preschool
  • Cilia / physiology
  • Cilia / ultrastructure
  • Female
  • Humans
  • Male
  • Microscopy, Electron
  • Movement
  • Nose / ultrastructure*
  • Recurrence
  • Respiratory Tract Infections / pathology*