The authors analyse the use of acetylcysteine as specific antidote treatment in 37 patients with acute 1,2-dichlorethane (DCE) poisoning. Administration of dichlorethane did not produce any determining effect on the outcome of the treatment in critical and irreversible concentration of DCE in the blood. The main component in complex therapy is early hemosorption. Acetylcystein may be used in the complex treatment of acute DCE intoxications after early extracorporal detoxication with the purpose of reducing the severity of troxic of hepatopathies.