Investigation of the polymorphic ScaI site by a PCR-based assay at the human atrial natriuretic peptides (hANP) gene locus

Hum Genet. 1992 Nov;90(3):323-4. doi: 10.1007/BF00220093.


The ScaI polymorphic site within the stop codon of the human atrial natriuretic peptides (hANP) gene was investigated in Mauritian Indian, black African and French Caucasian populations. A distinct distribution pattern is observed in these three populations.

MeSH terms

  • African Continental Ancestry Group / genetics
  • Animals
  • Atrial Natriuretic Factor / genetics*
  • Base Sequence
  • Chromosome Mapping
  • Chromosomes, Human, Pair 1*
  • Cricetinae
  • DNA, Single-Stranded
  • Deoxyribonucleases, Type II Site-Specific
  • Ethnic Groups / genetics
  • European Continental Ancestry Group / genetics
  • Gene Frequency
  • Humans
  • Hybrid Cells
  • Mauritius
  • Molecular Sequence Data
  • Polymerase Chain Reaction
  • Polymorphism, Genetic*


  • DNA, Single-Stranded
  • Atrial Natriuretic Factor
  • endodeoxyribonuclease ScaI
  • Deoxyribonucleases, Type II Site-Specific