Development of the human stria vascularis

Hear Res. 1992 Dec;64(1):39-51. doi: 10.1016/0378-5955(92)90166-k.

Abstract

Fifteen human fetal cochleas were investigated by light microscopy and transmission electron microscopy in order to observe the development of the stria vascularis. The earliest signs of strial cell differentiation take place during the 11th week of gestation. Subsequently, the first stages of the stria vascularis development occur quickly. At week 14 the three types of cells, namely, marginal, intermediate and basal cells are discernable. Moreover at this stage, signs of specific activity are already present. The adult-like appearance of the stria vascularis is reached by week 21 but its maturation is completed only during the last trimester of pregnancy. This is in good agreement both with the development of the organ of Corti structures and with the maturation of the human auditory function.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Cell Differentiation
  • Cochlear Duct / embryology*
  • Cochlear Duct / ultrastructure
  • Embryonic and Fetal Development
  • Gestational Age
  • Humans
  • Microscopy, Electron
  • Middle Aged
  • Organ of Corti / embryology
  • Stria Vascularis / cytology*
  • Stria Vascularis / ultrastructure