[Diagnosis and therapy of low-risk endometrial hyperplasia. Experience with LH-RH-A]

Minerva Ginecol. 1992 Dec;44(12):645-51.
[Article in Italian]

Abstract

Endometrial hyperplasia is a endometrial condition often found in perimenopausal age. AUB is the most frequent symptom of endometrial hyperplasia. The combination of hysteroscopy and endometrial biopsy is the most suitable approach for the diagnosis of endometrial hyperplasia in symptomatic patients. The Authors have studied endometrial modifications due to LH-RH analogue, a depot formula, in 60 perimenopausal patients with AUB and with hysteroscopic and histologic picture of low-risk endometrial hyperplasia. They report the result of treatment efficacy (disappearance of symptoms and tendency to hypoatrophy of the mucosa). The use of LH-RH A seems to have a good result in the management of oestrogen-dependent gynaecological benign diseases.

MeSH terms

  • Adult
  • Aged
  • Biopsy
  • Endometrial Hyperplasia / diagnosis
  • Endometrial Hyperplasia / drug therapy*
  • Endometrial Hyperplasia / pathology
  • Endometrium / pathology
  • Female
  • Gonadotropin-Releasing Hormone / analogs & derivatives*
  • Gonadotropin-Releasing Hormone / therapeutic use
  • Humans
  • Hysteroscopy
  • Middle Aged
  • Treatment Outcome
  • Triptorelin Pamoate* / analogs & derivatives*

Substances

  • Triptorelin Pamoate
  • Gonadotropin-Releasing Hormone
  • Tryptal