[Isoenzyme spectrum of lactate dehydrogenase, malate dehydrogenase, esterase and acid phosphatase of rat brain cells at different times after external 1 Gy gamma irradiation]

Radiobiologiia. 1992 Nov-Dec;32(6):815-9.
[Article in Russian]

Abstract

The influence of external single gamma-irradiation with a dose of 1 Gy on the isoenzyme composition of lactate dehydrogenase, malate dehydrogenase, esterase and acid phosphatase in the cytoplasm of rat brain cells has been investigated. Irradiation was shown to cause differently directed changes in the ratio of the isoenzymes under study at different times after exposure. The isoenzyme spectrum of lactate dehydrogenase and malate dehydrogenase was shown to be normalized on day 30 after irradiation, whereas the isoform composition of esterase and acid phosphatase was not stabilized at that time.

Publication types

  • Comparative Study
  • English Abstract

MeSH terms

  • Acid Phosphatase / analysis
  • Acid Phosphatase / radiation effects*
  • Animals
  • Brain / enzymology
  • Brain / radiation effects*
  • Densitometry
  • Esterases / analysis
  • Esterases / radiation effects*
  • Isoenzymes / analysis
  • Isoenzymes / radiation effects*
  • L-Lactate Dehydrogenase / analysis
  • L-Lactate Dehydrogenase / radiation effects*
  • Malate Dehydrogenase / analysis
  • Malate Dehydrogenase / radiation effects*
  • Male
  • Radiation Dosage
  • Rats
  • Rats, Wistar
  • Time Factors

Substances

  • Isoenzymes
  • L-Lactate Dehydrogenase
  • Malate Dehydrogenase
  • Esterases
  • Acid Phosphatase