Contrast nephropathy after coronary angiography

Mayo Clin Proc. 2004 Feb;79(2):211-9. doi: 10.4065/79.2.211.


Contrast nephropathy after coronary angiography is associated with considerable morbidity and mortality. We discuss the incidence, definition, and pathologic mechanisms of contrast nephropathy; provide an overview of risk factors; highlight proven preventive interventions; clarify which interventions have shown no benefit; and discuss future possibilities. The prevention of contrast nephropathy is crucial for the care of patients undergoing coronary angiography and should be possible with an understanding of risk factors and proven management strategies.

Publication types

  • Review

MeSH terms

  • Acetylcysteine / therapeutic use
  • Contrast Media / adverse effects*
  • Coronary Angiography*
  • Free Radical Scavengers / therapeutic use
  • Humans
  • Iatrogenic Disease* / prevention & control
  • Isotonic Solutions
  • Kidney Diseases / chemically induced*
  • Kidney Diseases / prevention & control
  • Osmolar Concentration
  • Risk Factors
  • Sodium Chloride / therapeutic use


  • Contrast Media
  • Free Radical Scavengers
  • Isotonic Solutions
  • Sodium Chloride
  • Acetylcysteine