Abstract
Primary infection with Pneumocystis carinii usually occurs early in life, and young infants receiving prolonged treatment with high-dose corticosteroids may be at risk for the development of symptomatic disease. Prophylaxis with trimethoprim-sulfamethoxazole is safe and effective and should be considered for such infants, particularly those with underlying airway abnormalities. We describe a 3-month-old immunocompetent infant who developed severe P carinii pneumonia after 6 weeks of high-dose corticosteroid therapy for cervicofacial and airway hemangiomas.
MeSH terms
-
Anti-Infective Agents / therapeutic use
-
Female
-
Glucocorticoids / administration & dosage
-
Glucocorticoids / adverse effects*
-
Glucocorticoids / therapeutic use
-
Head and Neck Neoplasms / drug therapy*
-
Hemangioma / drug therapy*
-
Humans
-
Infant
-
Pneumonia, Pneumocystis / chemically induced*
-
Pneumonia, Pneumocystis / immunology
-
Prednisolone / administration & dosage
-
Prednisolone / adverse effects*
-
Prednisolone / therapeutic use
-
Risk Factors
-
Trimethoprim, Sulfamethoxazole Drug Combination / therapeutic use
Substances
-
Anti-Infective Agents
-
Glucocorticoids
-
Trimethoprim, Sulfamethoxazole Drug Combination
-
Prednisolone