Bilateral Wallerian degeneration of the medial cerebellar peduncles after ponto-mesencephalic infarction

Eur J Radiol. 2004 Mar;49(3):198-203. doi: 10.1016/S0720-048X(03)00132-3.


Three patients with acute large paramedian ponto-mesencephalic infarctions developed a bilateral retrograde degeneration of the medial cerebellar peduncles within 4 months after the insult. In an initial magnetic resonance imaging (MRI) within the first 2 weeks, the medial cerebellar peduncles showed normal intensities, but a control MRI after 4 months showed bright hyperintensities in the T2-TSE weighted images, and moderately increased signal intensities in echo planar imaging-diffusion weighted imaging were seen, possibly representing bilateral Wallerian degeneration of the cerebellar-pontine fibers.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Brain Stem Infarctions / pathology*
  • Diffusion Magnetic Resonance Imaging / methods
  • Echo-Planar Imaging / methods
  • Female
  • Humans
  • Male
  • Middle Aged
  • Pons / pathology*
  • Tomography, X-Ray Computed / methods
  • Wallerian Degeneration / pathology*