Treatment of testosterone-induced gynecomastia with the aromatase inhibitor, anastrozole

E L Rhoden; A Morgentaler

doi:10.1038/sj.ijir.3901154

Treatment of testosterone-induced gynecomastia with the aromatase inhibitor, anastrozole

Int J Impot Res. 2004 Feb;16(1):95-7. doi: 10.1038/sj.ijir.3901154.

Authors

E L Rhoden¹, A Morgentaler

Affiliation

¹ Division of Urology, Beth Israel Deaconess Medical Center, Men's Health Boston, Harvard Medical School, Massachusetts 02445, USA. amorgent@caregroup.harvard.edu

PMID: 14963480
DOI: 10.1038/sj.ijir.3901154

Abstract

Gynecomastia is an unusual side effect associated with testosterone replacement therapy (TRT) that has been traditionally treated with surgery, radiation, or discontinuation of testosterone supplementation. We report here our experience with two cases of gynecomastia in men undergoing TRT who were successfully treated with the aromatase inhibitor anastrozole.

Publication types

Case Reports
Research Support, Non-U.S. Gov't

MeSH terms

Adult
Anastrozole
Androgens / adverse effects*
Aromatase Inhibitors
Enzyme Inhibitors / administration & dosage*
Gynecomastia / chemically induced*
Humans
Hypogonadism / drug therapy*
Male
Middle Aged
Nitriles / administration & dosage*
Testosterone / adverse effects*
Triazoles / administration & dosage*

Substances

Androgens
Aromatase Inhibitors
Enzyme Inhibitors
Nitriles
Triazoles
Anastrozole
Testosterone