The paper deals with analysis of pathogenesis features occurred in pathologically proliferative endometry (PPPE). Patient's state associated with PPPE is proposed to single out in a separate nosologic unit--dysplastic disease of endometry (DDE). Clinical and morphological classification of DDE is presented. DDE is regarded as the disease of an organism as in whole that suppose comprehensive approach to its diagnostics and treatment, forecasting further complications and carrying out adequate preventive measures. It assists in the improvement of diagnostic and treatment effectiveness of the disease, prevention of possible endometrium transformation in cancer.