Mechanisms of verbal memory impairment in four neurodevelopmental disorders

Brain Lang. 2004 Feb;88(2):180-9. doi: 10.1016/S0093-934X(03)00097-X.

Abstract

Profiles of verbal learning and memory performance were compared for typically developing children and for four developmental disorders characterized by different patterns of language functioning: specific language impairment, early focal brain damage, Williams Syndrome, and Down Syndrome. A list-learning task was used that allowed a detailed examination of the process of verbal learning, recall, and recognition (California Verbal Learning Test--Children's Version). Distinct patterns of performance characterized the four disorders. These patterns were consistent with the language deficits typically seen in the disorders, with the exception of a dissociation seen in Williams Syndrome.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adolescent
  • Brain / physiopathology*
  • Child
  • Down Syndrome / physiopathology
  • Female
  • Humans
  • Language Disorders / complications
  • Language Disorders / diagnosis*
  • Language Tests
  • Male
  • Memory Disorders / complications
  • Memory Disorders / diagnosis*
  • Memory Disorders / physiopathology*
  • Severity of Illness Index
  • Vocabulary*
  • Williams Syndrome / physiopathology