Patterning of the Drosophila nervous system: the achaete-scute gene complex

Trends Genet. 1992 Jun;8(6):202-8. doi: 10.1016/0168-9525(92)90234-u.


The genes of the achaete-scute complex (AS-C) confer on cells the ability to become neural precursors. Their expression is restricted to groups of cells, the proneural clusters, which occupy specific positions within the embryo neural anlagen and the larva imaginal discs. Neuroblasts or sensory organ mother cells are born within these clusters. Thus, the patterns of expression of the AS-C genes help to define the topology of the nervous system.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Cell Communication
  • Chromosome Mapping
  • Drosophila melanogaster / embryology*
  • Drosophila melanogaster / genetics
  • Gene Expression Regulation
  • Genes
  • Nervous System / embryology*
  • Sex Determination Analysis
  • Wings, Animal / embryology