The effects of home-based resistance exercise on balance, power, and mobility in adults with multiple sclerosis

Arch Phys Med Rehabil. 2004 Feb;85(2):290-7. doi: 10.1016/j.apmr.2003.06.003.


Objective: To examine the effects of an 8-week home-based resistance exercise program on balance, power, and mobility in adults with multiple sclerosis.

Design: Experimental group design.

Setting: General community.

Participants: Twenty-nine women (age, 50.3+/-8.5 y) and 8 men (age, 51.1+/-7.1 y) were stratified by disability level and age and were randomized into exercise (n=19) and control (n=17) groups.

Intervention: The exercise group had lower-extremity resistance training 3 times a week. The control group maintained current level of physical activity.Main outcome measures Primary outcome measures included balance, as measured by anteroposterior sway, mediolateral sway, and sway velocity using the AccuSway(PLUS) force platform; mobility as assessed with the Up and Go test; and leg power as assessed with the Leg Extensor Power Rig.

Results: Leg extensor power improved significantly in the exercise group (pretest, 3.19+/-1.36 W/kg; posttest, 3.95+/-1.23 W/kg; P=.004), although measures of balance and mobility did not change.

Conclusions: The home-based resistance program was well tolerated by participants and offered a practical means to improve leg extensor power in a short period of time.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Analysis of Variance
  • Exercise / physiology*
  • Female
  • Humans
  • Leg / physiology
  • Locomotion / physiology*
  • Male
  • Middle Aged
  • Multiple Sclerosis / physiopathology
  • Multiple Sclerosis / rehabilitation*
  • Muscle, Skeletal / physiopathology*
  • Postural Balance / physiology*