The French early arthritis registry

Clin Exp Rheumatol. 2003 Sep-Oct;21(5 Suppl 31):S123-8.


This report is focused on two French multicenter cohorts of patients with early rheumatoid arthritis (RA). The first one is a community-based study which was started in 1993. It was mainly designed to identify prognostic factors of joint destruction, disability and remission in patients with early RA. The 3-year and 5-year results have been recently reported. Briefly, progression of joint damage was best predicted at baseline by radiographic scores, ESR, CRP, rheumatoid factor and DRB1*04 genes, and disability by disease activity including the HAQ score. Recently, the French Society of Rheumatology initiated a large national multicenter registry (800 patients), the "ESPOIR cohort study", that could serve as a database to allow investigations not only on diagnostic and prognostic markers, but also on etiologic, pathogenic and medico-economic factors among patients with early inflammatory arthritis who could later develop RA. The objectives, design and organization of this early arthritis registry are described.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Activities of Daily Living
  • Adult
  • Age Distribution
  • Aged
  • Arthritis, Rheumatoid / diagnosis*
  • Arthritis, Rheumatoid / epidemiology*
  • Arthritis, Rheumatoid / therapy
  • Combined Modality Therapy / methods
  • Cross-Sectional Studies
  • Disability Evaluation*
  • Female
  • France / epidemiology
  • Humans
  • Incidence
  • Joint Deformities, Acquired / diagnosis
  • Joint Deformities, Acquired / epidemiology*
  • Male
  • Middle Aged
  • Multicenter Studies as Topic
  • Pain Measurement
  • Prognosis
  • Range of Motion, Articular / physiology
  • Registries*
  • Risk Factors
  • Severity of Illness Index
  • Sex Distribution