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. 2004 Jun 12;20(9):1466-7.
doi: 10.1093/bioinformatics/bth092. Epub 2004 Feb 19.

TANDEM: Matching Proteins With Tandem Mass Spectra


TANDEM: Matching Proteins With Tandem Mass Spectra

Robertson Craig et al. Bioinformatics. .


Summary: Tandem mass spectra obtained from fragmenting peptide ions contain some peptide sequence specific information, but often there is not enough information to sequence the original peptide completely. Several proprietary software applications have been developed to attempt to match the spectra with a list of protein sequences that may contain the sequence of the peptide. The application TANDEM was written to provide the proteomics research community with a set of components that can be used to test new methods and algorithms for performing this type of sequence-to-data matching.

Availability: The source code and binaries for this software are available at, for Windows, Linux and Macintosh OSX. The source code is made available under the Artistic License, from the authors.

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