Antifungal activity of some bis-5-methylbenzimidazole compounds

H Küçükbay; R Durmaz; N Okyucu; S Günal

doi:10.1007/BF02993478

Antifungal activity of some bis-5-methylbenzimidazole compounds

Folia Microbiol (Praha). 2003;48(5):679-81. doi: 10.1007/BF02993478.

Authors

H Küçükbay¹, R Durmaz, N Okyucu, S Günal

Affiliation

¹ Department of Chemistry, Faculty of Arts and Sciences, Inönü University, 44069 Malatya, Turkey. hkucukbay@inonu.edu.tr

PMID: 14976728
DOI: 10.1007/BF02993478

Abstract

Twenty bis-5-methylbenzimidazole compounds were evaluated for their in vitro antifungal activity against Candida albicans and Candida tropicalis. Except for three all compounds exhibited an antifungal activity against these yeasts over a range of the minimum inhibitory concentration (MIC) between 25 and 800 mg/L.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Antifungal Agents / chemistry
Antifungal Agents / pharmacology*
Benzimidazoles / chemistry
Benzimidazoles / pharmacology*
Candida albicans / drug effects*
Candida tropicalis / drug effects*
Microbial Sensitivity Tests

Substances

Antifungal Agents
Benzimidazoles