A preliminary study of the Kiddie Schedule for Affective Disorders and Schizophrenia for School-Age Children mania rating scale for children and adolescents

J Child Adolesc Psychopharmacol. Winter 2003;13(4):463-70. doi: 10.1089/104454603322724850.


Objective: To construct a mania rating scale designed for children and adolescents.

Methods: Fourteen questions from the Kiddie Schedule for Affective Disorders and Schizophrenia for School-Age Children-Present Episode (K-SADS-P) 1986 version plus a new item assessing mood lability were used to construct a clinician-rated mania rating scale (K-SADS-MRS). Interrater reliability was determined prospectively with 22 patients from a bipolar outpatient clinic. Sensitivity to treatment effects was determined in a separate cohort of 23 patients.

Results: Internal consistency (Cronbach's alpha = 0.94) and interrater reliability (intraclass correlation coefficient = 0.97 between two raters) were high. Convergent validity with the Clinical Global Impressions-Severity scale (bipolar version) was good (r(s)= 0.91, p < 0.001). Treatment responders had significantly greater reduction in K-SADS-MRS scores than nonresponders (-15.6 +/- 8.7 vs. 0.3 +/- 8.8), t(21) = 4.2, p < 0.001. The K-SADS-MRS scores differentiated bipolar patients who had clinically significant manic symptoms from those who did not, with a sensitivity of 87% and a specificity of 81%.

Conclusion: The K-SADS-MRS shows promise as a rating scale for measuring manic symptom severity in pediatric bipolar patients.

Publication types

  • Clinical Trial
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adolescent
  • Affect
  • Bipolar Disorder / diagnosis*
  • Bipolar Disorder / psychology*
  • Child
  • Female
  • Humans
  • Male
  • Mood Disorders / diagnosis*
  • Mood Disorders / drug therapy
  • Mood Disorders / psychology*
  • Observer Variation
  • Prospective Studies
  • Psychiatric Status Rating Scales*
  • Reproducibility of Results
  • Schizophrenia / diagnosis*
  • Schizophrenia / drug therapy
  • Schizophrenic Psychology*