EEG patterns in persons exposed to ionizing radiation as a result of the chernobyl accident. Part 2: quantitative EEG analysis in patients who had acute radiation sickness

J Neuropsychiatry Clin Neurosci. 2004 Winter;16(1):70-82. doi: 10.1176/jnp.16.1.70.


Cross-sectional quantitative electroencephalogram (qEEG) study (1996-2001) among Chernobyl accident survivors, who had confirmed acute radiation sickness and were irradiated in dose of 1-5 Gy, revealed the neurophysiological markers of ionizing radiation. Neuropsychological markers were: left fronto-temporal dominant frequency reduction; absolute delta-power lateralization to the left (dominant) hemisphere; relative delta-power increase in the fronto-temporal areas; absolute theta-power decrease in the left temporal region; absolute and relative alpha-power diffusive decrease, which may reflect cortico-limbic dysfunction lateralized to the left, dominant hemisphere, with the fronto-temporal cortical and hippocampal damage. Quantitative electroencephalogram proposed for differentiation of radiation and nonradiation brain damages and as a new biological dosymetry method. High radiosensitivity of the brain, neocortex, and dominant hemisphere higher radiosensitivity are discussed.

Publication types

  • Comparative Study

MeSH terms

  • Brain Mapping
  • Cerebral Cortex / abnormalities
  • Cerebral Cortex / physiopathology
  • Cerebral Cortex / radiation effects*
  • Cross-Sectional Studies
  • Dose-Response Relationship, Radiation
  • Electroencephalography
  • Female
  • Functional Laterality / physiology
  • Humans
  • Longitudinal Studies
  • Male
  • Radiation Injuries / epidemiology
  • Radiation Injuries / physiopathology*
  • Radiation, Ionizing
  • Radioactive Hazard Release*
  • Russia