Molecular genetics of human cognition

Mol Interv. 2002 Oct;2(6):376-91, 339. doi: 10.1124/mi.2.6.376.

Abstract

Our understanding of the molecular underpinnings of human cognition has been greatly aided by the convergent synergy of clinical, genetic, and signaling research. By identifying the mutated genes that give rise to syndromes of mental retardation or cognitive defects in patients, and by placing the associated gene products within signaling networks, researchers are piecing together how learning occurs and how memories are formed and sustained.

Publication types

  • Review

MeSH terms

  • Angelman Syndrome / genetics
  • Angelman Syndrome / metabolism
  • Animals
  • Coffin-Lowry Syndrome / genetics
  • Coffin-Lowry Syndrome / metabolism
  • Cognition / physiology*
  • Dendrites / pathology
  • Down Syndrome / genetics
  • Fragile X Syndrome / genetics
  • Fragile X Syndrome / metabolism
  • Genetics, Medical*
  • Humans
  • Memory / physiology
  • Mice
  • Mutation
  • Myotonic Dystrophy / genetics
  • Myotonic Dystrophy / metabolism
  • Neurofibromatoses / genetics
  • Neurofibromatoses / metabolism
  • Rett Syndrome / genetics
  • Rett Syndrome / metabolism
  • Rubinstein-Taybi Syndrome / genetics
  • Rubinstein-Taybi Syndrome / metabolism
  • Williams Syndrome / genetics
  • Williams Syndrome / metabolism