Targeting the Checkpoint Kinases: Chemosensitization Versus Chemoprotection

Nat Rev Cancer. 2004 Mar;4(3):216-25. doi: 10.1038/nrc1296.

Publication types

  • Review

MeSH terms

  • Anticarcinogenic Agents / classification
  • Anticarcinogenic Agents / therapeutic use*
  • Anticarcinogenic Agents / toxicity
  • Antineoplastic Agents / classification
  • Antineoplastic Agents / therapeutic use*
  • Antineoplastic Agents / toxicity
  • Checkpoint Kinase 2
  • DNA Damage / genetics
  • Genes, Tumor Suppressor
  • Humans
  • Neoplasms / drug therapy*
  • Neoplasms / genetics
  • Neoplasms / prevention & control*
  • Protein Kinases / metabolism*
  • Protein-Serine-Threonine Kinases / genetics
  • Protein-Serine-Threonine Kinases / metabolism

Substances

  • Anticarcinogenic Agents
  • Antineoplastic Agents
  • Protein Kinases
  • Checkpoint Kinase 2
  • CHEK2 protein, human
  • Protein-Serine-Threonine Kinases