Abstract
Genetic analyses of nuclear distribution mutants have indicated that functions of the microtubule motor, cytoplasmic dynein, and its regulators are important for nuclear positioning in filamentous fungi. Here we review these studies and also present the need to further dissect how dynein and its associated microtubule cytoskeleton are involved mechanistically in nuclear positioning in the multinucleated hyphae.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, Non-P.H.S.
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Review
MeSH terms
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Aspergillus nidulans / cytology
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Aspergillus nidulans / physiology*
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Aspergillus nidulans / ultrastructure
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Cell Nucleus / physiology*
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Dyneins / genetics
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Dyneins / physiology
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Fungal Proteins / genetics
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Fungal Proteins / physiology
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Fungi / cytology
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Fungi / physiology*
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Fungi / ultrastructure
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Genes, Fungal
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Kinesin / genetics
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Kinesin / physiology
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Microtubules / genetics
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Microtubules / physiology
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Molecular Motor Proteins / genetics
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Molecular Motor Proteins / physiology
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Morphogenesis
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Movement
Substances
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Fungal Proteins
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Molecular Motor Proteins
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Dyneins
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Kinesin