In vivo human retinal imaging by ultrahigh-speed spectral domain optical coherence tomography

Opt Lett. 2004 Mar 1;29(5):480-2. doi: 10.1364/ol.29.000480.


An ultrahigh-speed spectral domain optical coherence tomography (SD-OCT) system is presented that achieves acquisition rates of 29,300 depth profiles/s. The sensitivity of SD-OCT and time domain OCT (TD-OCT) are experimentally compared, demonstrating a 21.7-dB improvement of SD-OCT over TD-OCT. In vivo images of the human retina are presented, demonstrating the ability to acquire high-quality structural images with an axial resolution of 6 microm at ultrahigh speed and with an ocular exposure level of less than 600 microW.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Humans
  • Models, Theoretical*
  • Retina / anatomy & histology*
  • Time Factors
  • Tomography, Optical Coherence* / instrumentation
  • Tomography, Optical Coherence* / methods