Identifying transcriptional targets

Genome Biol. 2004;5(3):210. doi: 10.1186/gb-2004-5-3-210. Epub 2004 Feb 27.

Abstract

Identifying the targets of transcription factors is important for understanding cellular processes. We review how targets have previously been isolated and outline new technologies that are being developed to identify novel direct targets, including chromatin immunoprecipitation combined with microarray screening and bioinformatic approaches.

Publication types

  • Review

MeSH terms

  • Animals
  • Binding Sites / genetics
  • DNA / genetics*
  • DNA / metabolism
  • Humans
  • Transcription Factors / genetics*
  • Transcription Factors / metabolism

Substances

  • Transcription Factors
  • DNA