Impact of previous multiple portoenterostomies on living donor liver transplantation for biliary atresia

Hepatogastroenterology. Jan-Feb 2004;51(55):192-4.

Abstract

Background/aims: The present study examined the impact of portoenterostomy on the morbidity and mortality of patients who later underwent living donor liver transplantation for biliary atresia.

Methodology: Sixty-one consecutive patients from January 1996 to May 2001 were analyzed. They were divided into two groups according to the number of previous portoenterostomies: once (group A, n=26) and twice or more (group B, n=35). Preoperative status, mortality, morbidity, hospital duration and survival were examined and compared between the groups.

Results: Preoperative parameters regarding liver function and urgency status were comparable between the groups. The operation duration tended to be longer in group B than in group A (p=0.07). The blood loss and transfusion volumes in group B were greater than those in group A (p=0.03 for both comparisons). Vascular complications tended to be more frequent in group B patients. However, this difference was not significant (12% vs. 29%, p=0.06). The duration of hospitalization was longer in group B (p=0.04). Survival rates were comparable between the groups.

Conclusions: Our surgical results suggest that multiple previous portoenterostomies might have negative short-term effects in patients who undergo living donor liver transplantation for biliary atresia.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biliary Atresia / surgery*
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Length of Stay
  • Liver Transplantation*
  • Living Donors
  • Male
  • Portoenterostomy, Hepatic*
  • Reoperation
  • Treatment Outcome