A prospective, pilot study of treatment of amblyopia in children 10 to <18 years old

Am J Ophthalmol. 2004 Mar;137(3):581-3. doi: 10.1016/j.ajo.2003.08.043.


Purpose: To determine whether amblyopia can be successfully treated in older children and adolescents.

Design: Prospective, single group treatment trial.

Methods: Sixty-six amblyopic patients aged 10 to <18 years with amblyopic eye acuity of 20/40 to 20/160 were treated with daily patching (> or =2 hours a day) combined with at least 1 hour of near activities. Visual acuity was measured before and after 2 months of prescribed treatment.

Results: Visual acuity improved 2 or more lines from baseline in 18 (27%) of the 66 patients (95% confidence interval, 17%-40%), and the improvement appeared similar in 10- to <14-year-olds and 14- to <18-year-olds.

Conclusions: Amblyopia treatment can improve visual acuity in older children and adolescents. A randomized controlled trial is needed to determine if there is an upper age limit for which amblyopia treatment is successful.

Publication types

  • Clinical Trial
  • Multicenter Study
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adolescent
  • Amblyopia / therapy*
  • Child
  • Humans
  • Pilot Projects
  • Prospective Studies
  • Sensory Deprivation*
  • Visual Acuity / physiology