Diffuse spinal and intercostal nerve involvement in chronic inflammatory demyelinating polyradiculoneuropathy: MRI findings

Eur Radiol. 2003 Dec;13 Suppl 4:L230-4. doi: 10.1007/s00330-003-1996-3.


Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is an uncommon demyelinating disorder with a relapsing and remitting or continuously progressive course. Hypertrophic nerve roots, sometimes associated with gadolinium enhancement, has been reported more commonly in lumbar spine and less commonly in the brachial plexus and cervical roots; however, diffuse involvement of intercostal nerves bilaterally has never been reported previously. We present MRI findings which include diffuse enlargement and mild enhancement of roots and extraforaminal segments of nerves in all segments except a short segment between T12-L2 as well as all the intercostal nerves in a case of CIPD with a 10-year history.

Publication types

  • Case Reports

MeSH terms

  • Biopsy, Needle
  • Electrophysiology
  • Follow-Up Studies
  • Humans
  • Immunohistochemistry
  • Intercostal Nerves / pathology*
  • Magnetic Resonance Imaging / methods*
  • Male
  • Middle Aged
  • Polyradiculoneuropathy, Chronic Inflammatory Demyelinating / diagnosis*
  • Polyradiculoneuropathy, Chronic Inflammatory Demyelinating / physiopathology
  • Sensitivity and Specificity
  • Severity of Illness Index
  • Spinal Nerve Roots / pathology*