Abstract
A novel actin-binding protein, Shroom, localises to precisely those cells that will constrict during cranial neural tube closure and appears pivotal in regulating the apical constrictions that drive epithelial foldings in vertebrate embryos.
MeSH terms
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Actins / metabolism
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Animals
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Central Nervous System / embryology*
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Central Nervous System / metabolism
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Epithelium / embryology
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Gene Expression Regulation*
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Mice / embryology*
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Microfilament Proteins / genetics
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Microfilament Proteins / metabolism*
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Morphogenesis / genetics
Substances
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Actins
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Microfilament Proteins
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Shrm protein, mouse