Membrane fusion: caught in a trap

Benjamin Short; Francis A Barr

doi:10.1016/j.cub.2004.02.017

Membrane fusion: caught in a trap

Curr Biol. 2004 Mar 9;14(5):R187-9. doi: 10.1016/j.cub.2004.02.017.

Authors

Benjamin Short¹, Francis A Barr

Affiliation

¹ Department of Cell Biology, Max-Planck-Institute of Biochemistry, Am Klopferspitz 18, Martinsried, 82152 Germany. short@biochem.mpg.de

PMID: 15028233
DOI: 10.1016/j.cub.2004.02.017

Abstract

SNAREs are small coiled-coil proteins required for specific membrane fusion events in eukaryotic cells. Recent evidence points to the existence of an inhibitory class of SNAREs, i-SNAREs, which prevent incorrect fusions from occurring, adding a further layer of regulation to the process of membrane docking and fusion.

Publication types

Review

MeSH terms

Golgi Apparatus / metabolism
Liposomes / metabolism
Membrane Fusion / physiology*
Membrane Proteins / antagonists & inhibitors*
Membrane Proteins / metabolism*
Membrane Proteins / physiology
SNARE Proteins
Vesicular Transport Proteins*
rab GTP-Binding Proteins / metabolism

Substances

Liposomes
Membrane Proteins
SNARE Proteins
Vesicular Transport Proteins
rab GTP-Binding Proteins