Possible central nervous system infection by SARS coronavirus

Emerg Infect Dis. 2004 Feb;10(2):342-4. doi: 10.3201/eid1002.030638.


On day 22 of illness, generalized tonic-clonic convulsion developed in a 32-year-old woman with severe acute respiratory syndrome (SARS). Cerebrospinal fluid tested positive for SARS coronavirus (SARS-CoV) by reverse transcriptase-polymerase chain reaction. SARS-CoV may have caused an infection in the central nervous system in this patient.

Publication types

  • Case Reports

MeSH terms

  • Acute Kidney Injury / complications
  • Adult
  • Central Nervous System Infections / complications*
  • Central Nervous System Infections / diagnosis
  • Central Nervous System Infections / virology
  • Female
  • Humans
  • Pregnancy
  • Pregnancy Complications, Infectious / virology
  • Reverse Transcriptase Polymerase Chain Reaction
  • Severe Acute Respiratory Syndrome / complications*
  • Severe Acute Respiratory Syndrome / virology
  • Severe acute respiratory syndrome-related coronavirus / genetics
  • Severe acute respiratory syndrome-related coronavirus / isolation & purification