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. 2004 Apr 1;159(7):702-6.
doi: 10.1093/aje/kwh090.

A Modified Poisson Regression Approach to Prospective Studies With Binary Data

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A Modified Poisson Regression Approach to Prospective Studies With Binary Data

Guangyong Zou. Am J Epidemiol. .

Abstract

Relative risk is usually the parameter of interest in epidemiologic and medical studies. In this paper, the author proposes a modified Poisson regression approach (i.e., Poisson regression with a robust error variance) to estimate this effect measure directly. A simple 2-by-2 table is used to justify the validity of this approach. Results from a limited simulation study indicate that this approach is very reliable even with total sample sizes as small as 100. The method is illustrated with two data sets.

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