The potential danger of COX-2 inhibitors

Fertil Steril. 2004 Mar;81(3):493-4. doi: 10.1016/j.fertnstert.2003.10.016.

Abstract

Cyclooxygenase (COX)-2 inhibitors have a major effect on ovulation and may impair fertilization, decidualization, implantation, and parturition, as well as female fertility. Women attempting to become pregnant need to pay more attention to their use of COX-2 inhibitors.

MeSH terms

  • Animals
  • Cyclooxygenase 2
  • Cyclooxygenase 2 Inhibitors
  • Cyclooxygenase Inhibitors / adverse effects*
  • Female
  • Humans
  • Isoenzymes / antagonists & inhibitors*
  • Membrane Proteins
  • Ovulation / drug effects
  • Prostaglandin Antagonists / adverse effects
  • Prostaglandin-Endoperoxide Synthases

Substances

  • Cyclooxygenase 2 Inhibitors
  • Cyclooxygenase Inhibitors
  • Isoenzymes
  • Membrane Proteins
  • Prostaglandin Antagonists
  • Cyclooxygenase 2
  • PTGS2 protein, human
  • Prostaglandin-Endoperoxide Synthases