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. 2004 Feb;2(2):123-40.
doi: 10.1038/nrmicro818.

Pathogenic Escherichia Coli


Pathogenic Escherichia Coli

James B Kaper et al. Nat Rev Microbiol. .


Few microorganisms are as versatile as Escherichia coli. An important member of the normal intestinal microflora of humans and other mammals, E. coli has also been widely exploited as a cloning host in recombinant DNA technology. But E. coli is more than just a laboratory workhorse or harmless intestinal inhabitant; it can also be a highly versatile, and frequently deadly, pathogen. Several different E. coli strains cause diverse intestinal and extraintestinal diseases by means of virulence factors that affect a wide range of cellular processes.

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