Long-term prognosis of patients with obstructing carcinoma of the right colon

Am J Surg. 2004 Apr;187(4):497-500. doi: 10.1016/j.amjsurg.2003.12.028.

Abstract

Background: The long-term prognosis of patients with colon cancer is dependent on many factors. The aim of this retrospective study was to assess the long-term prognosis of patients with obstructing carcinoma of the right colon.

Methods: From 1981 to 1988, 256 patients at the Veterans General Hospital-Taipei who were status postcurative resection of right colon adenocarcinoma were classified as obstruction group (n = 35) or nonobstruction group (n = 221) as appropriate.

Results: Analysis revealed no differences in age, sex, tumor location, or stage (P >0.05) between the two groups. However, the overall and distant recurrence rates were significant higher in obstructed patients than in nonobstructed patients. Further, long-term crude and cancer-specific survival rates were significantly lower in obstructed patients when examining either overall patient outcome or stage-matched outcomes. Multivariate analysis demonstrated that obstruction and tumor stage were both independent prognostic factors.

Conclusions: Obstruction status was an independent prognostic factor for patients with right colon carcinoma. The long-term prognosis of patients with obstructing carcinoma of the right colon was poor.

MeSH terms

  • Adenocarcinoma / complications*
  • Adenocarcinoma / mortality
  • Adenocarcinoma / surgery
  • Aged
  • Colonic Diseases / etiology*
  • Colonic Neoplasms / complications*
  • Colonic Neoplasms / mortality
  • Colonic Neoplasms / surgery
  • Female
  • Humans
  • Intestinal Obstruction / etiology*
  • Male
  • Prognosis
  • Retrospective Studies
  • Survival Rate
  • Time Factors