N-Acyl derivatives of Asn, new bacterial N-acyl D-amino acids with surfactant activity

Amino Acids. 2004 Mar;26(2):209-14. doi: 10.1007/s00726-003-0056-2. Epub 2003 Dec 22.

Abstract

New N-acyl D-amino acids were isolated from Bacillus pumilus IM 1801. Their structures were determined by chemical analysis and mass spectrometry. The lipid part was identified as a mixture of fatty acids with 11, 12, 13, 15, and 16 carbon atoms in the iso, anteiso or n configuration linked by an amide bond with a D-asparagine. They exhibited surfactant properties.

MeSH terms

  • Amino Acids / chemistry*
  • Amino Acids / isolation & purification
  • Asparagine / analogs & derivatives*
  • Asparagine / chemistry*
  • Bacillus / chemistry*
  • Chromatography, High Pressure Liquid
  • Fatty Acids / chemistry
  • Spectrometry, Mass, Electrospray Ionization / methods
  • Surface-Active Agents / chemistry*
  • Surface-Active Agents / isolation & purification
  • Time Factors

Substances

  • Amino Acids
  • Fatty Acids
  • Surface-Active Agents
  • Asparagine