Metastatic spine tumors

South Med J. 2004 Mar;97(3):246-53. doi: 10.1097/01.SMJ.0000053923.35326.0D.


Cancer is the second leading cause of death in the United States, and vertebral body metastases often occur in systemic malignancy. Metastatic spinal tumors may present with pain or neurologic deficit, or may be detected during screening examinations in patients with known malignancy. Management of spinal metastases remains controversial. The role of surgery, especially decompressive laminectomy without stabilization, has been questioned. Recent series attest to the beneficial role of surgery, emphasizing anterior and combined decompression and stabilization procedures. We review the relevant literature on metastatic spinal tumors, assessing imaging strategies, adjuvant treatment, patient selection, and results and complications. Operative decompression and stabilization is an important tool in the management of spinal metastatic disease. Patient selection and appropriate use of anterior and/or posterior decompression and stabilization are necessary to optimize surgical results.

Publication types

  • Review

MeSH terms

  • Blood Loss, Surgical
  • Chemotherapy, Adjuvant
  • Decompression, Surgical*
  • Humans
  • Laminectomy
  • Monitoring, Intraoperative
  • Postoperative Care
  • Radiotherapy, Adjuvant
  • Spinal Neoplasms / radiotherapy
  • Spinal Neoplasms / secondary*
  • Spinal Neoplasms / surgery*
  • Tomography, X-Ray Computed
  • Treatment Outcome