A genetic algorithm for the detection of new cis-regulatory modules in sets of coregulated genes

Bioinformatics. 2004 Aug 12;20(12):1974-6. doi: 10.1093/bioinformatics/bth179. Epub 2004 Mar 25.


Summary: The implementation of a genetic algorithm is described that provides a fast method of searching for the optimal combination of transcription factor binding sites in a set of regulatory sequences.

Availability: The algorithm can be used transparently as a web service from within the Toucan software. Toucan can be accessed at http://www.esat.kuleuven.ac.be/~saerts/software/toucan.php. A standalone version of the software is available upon request.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms*
  • Chromosome Mapping / methods*
  • Gene Expression Profiling / methods*
  • Gene Expression Regulation / genetics*
  • Genes, Regulator / genetics*
  • Models, Genetic
  • Sequence Alignment / methods*
  • Sequence Analysis, DNA / methods*
  • Software