Abstract
Macrolide resistance in 156 consecutive group B streptococcal isolates was investigated. Thirty-five isolates (22.4%) had inducible (80%) or constitutive (20%) erythromycin resistance. The genes responsible were erm(B), erm(A) subclass erm(TR), and erm(B) plus erm(TR) in 62.9, 2.9, and 8.6% of isolates, respectively. Nine isolates (25.7%) harbored neither mef nor detectable erm genes.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adult
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Anti-Bacterial Agents / pharmacology*
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Clindamycin / pharmacology
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Drug Resistance, Bacterial / genetics
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Erythromycin / pharmacology
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Female
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Genes, Bacterial / genetics
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Genes, Bacterial / physiology
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Humans
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Macrolides / pharmacology*
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Microbial Sensitivity Tests
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Rectum / microbiology
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Streptococcal Infections / epidemiology
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Streptococcal Infections / microbiology
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Streptococcus agalactiae / drug effects*
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Streptococcus agalactiae / genetics*
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Turkey / epidemiology
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Vagina / microbiology
Substances
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Anti-Bacterial Agents
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Macrolides
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Clindamycin
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Erythromycin