Structures of the lectins from Pseudomonas aeruginosa: insight into the molecular basis for host glycan recognition

Microbes Infect. 2004 Feb;6(2):221-8. doi: 10.1016/j.micinf.2003.10.016.


The opportunistic human pathogen Psuedomonas aeruginosa produces two lectins in close association with virulence factors: PA-IL adn PA-IIL, which bind to galactose- and fucose/mannose-containing glycoconjugates, respectively. We review here the structural aspects of these lectins relative to their putative roles in host recognition, cell surface adhesion and biofilm formation.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Adhesins, Bacterial / chemistry
  • Adhesins, Bacterial / immunology*
  • Glycoproteins / chemistry
  • Glycoproteins / metabolism*
  • Lectins / chemistry
  • Lectins / immunology*
  • Pseudomonas aeruginosa / immunology
  • Pseudomonas aeruginosa / metabolism*
  • Receptors, Immunologic / immunology


  • Adhesins, Bacterial
  • Glycoproteins
  • Lectins
  • Receptors, Immunologic
  • adhesin, Pseudomonas