Toxicity of concentrated sodium hypochlorite used as an endodontic irrigant

Int Endod J. 2004 Apr;37(4):272-80. doi: 10.1111/j.0143-2885.2004.00804.x.

Abstract

Aim: To present a clinical case that illustrates the toxicity of concentrated sodium hypochlorite (NaOCl) on vital tissues.

Summary: The severe clinical consequences of extruding concentrated NaOCl into the periradicular tissues during root canal irrigation are described. After diagnosis of external resorption in tooth 34, endodontic treatment was initiated. Following irrigation with a concentrated NaOCl solution, a rapidly developing swelling and haematoma were visible. During the next few days, an extensive bruise and local necrosis of the oral mucosa developed. After healing of the involved tissues, the canal was prepared and obturated. At this time, no clinical symptoms remained.

Key learning points: * The use of concentrated NaOCl as a root canal irrigant might cause severe clinical problems when extruded into vital tissues. * The present report confirms the known toxicity of NaOCl to soft tissues following inadvertent extrusion. * To avoid extrusion, it is always prudent to confirm the length and integrity of the root canal system before irrigating with concentrated solutions.

Publication types

  • Case Reports

MeSH terms

  • Dental Pulp Cavity / anatomy & histology
  • Extravasation of Diagnostic and Therapeutic Materials / complications
  • Extravasation of Diagnostic and Therapeutic Materials / etiology
  • Female
  • Hematoma / chemically induced
  • Humans
  • Lip / drug effects*
  • Lip / injuries
  • Lip / pathology
  • Middle Aged
  • Mouth Mucosa / drug effects*
  • Mouth Mucosa / injuries
  • Mouth Mucosa / pathology
  • Necrosis
  • Odontometry
  • Root Canal Irrigants / administration & dosage
  • Root Canal Irrigants / adverse effects*
  • Root Resorption / complications
  • Sodium Hypochlorite / administration & dosage
  • Sodium Hypochlorite / adverse effects*

Substances

  • Root Canal Irrigants
  • Sodium Hypochlorite