Evaluation of a new generation of plastic evacuated blood-collection tubes in clinical chemistry, therapeutic drug monitoring, hormone and trace metal analysis

Clin Chem Lab Med. 2004 Jan;42(1):67-71. doi: 10.1515/CCLM.2004.013.


Polyethylene terephthalate (PET) tubes have several advantages over glass tubes: they are unbreakable, lighter and more easily disposed of. Despite a steady increase in their use and an expansion of the range of available tubes, few studies validating their use have been published in the literature. This paper describes the various studies that have been performed to compare VENOJECT glass, VENOSAFE PET and VENOSAFE PET/heparin tubes for the assay of a panel of analytes in routine clinical chemistry, immunochemistry, hormone and tumor marker analysis and trace metal determination. These studies demonstrate that VENOSAFE PET tubes are a suitable alternative to glass tubes.

Publication types

  • Evaluation Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Blood Specimen Collection / instrumentation*
  • Blood Specimen Collection / methods*
  • Clinical Chemistry Tests / instrumentation*
  • Clinical Chemistry Tests / methods*
  • Drug Monitoring / instrumentation*
  • Drug Monitoring / methods
  • Glass
  • Heparin
  • Hormones / blood*
  • Humans
  • Metals / analysis
  • Metals / blood*
  • Polyethylene Terephthalates / analysis
  • Polyethylene Terephthalates / chemistry
  • Water / chemistry


  • Hormones
  • Metals
  • Polyethylene Terephthalates
  • Water
  • Heparin