Dissemination of a clone of unusual phenotype of pandrug-resistant Acinetobacter baumannii at a university hospital in Taiwan

J Clin Microbiol. 2004 Apr;42(4):1759-63. doi: 10.1128/JCM.42.4.1759-1763.2004.

Abstract

From December 2002 to February 2003, 15 isolates of pandrug-resistant unidentified Acinetobacter species were recovered from seven patients treated on different wards or intensive care units. Both 16S-23S rRNA intergenic spacer PCR-restriction fragment length polymorphism profiles and sequence analysis of these isolates identified them as Acinetobacter baumannii. This pandrug-resistant A. baumannii strain with an unusual phenotype could persist in humans for long periods and was widely disseminated throughout the hospital.

MeSH terms

  • Acinetobacter Infections / microbiology
  • Acinetobacter Infections / transmission*
  • Acinetobacter baumannii / classification
  • Acinetobacter baumannii / drug effects
  • Acinetobacter baumannii / genetics*
  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Cross Infection / microbiology
  • Cross Infection / transmission*
  • DNA, Ribosomal Spacer
  • Drug Resistance, Multiple, Bacterial / genetics*
  • Female
  • Hospitals, University*
  • Humans
  • Intensive Care Units
  • Male
  • Middle Aged
  • Polymerase Chain Reaction
  • Polymorphism, Restriction Fragment Length
  • RNA, Ribosomal, 16S / genetics
  • RNA, Ribosomal, 23S / genetics
  • Sequence Analysis, DNA
  • Taiwan / epidemiology

Substances

  • DNA, Ribosomal Spacer
  • RNA, Ribosomal, 16S
  • RNA, Ribosomal, 23S